Dr. Maria Cristina Guglielmo has degree in Medical Biotechnologies at the University of Rome “ La Sapienza”. She completed her PhD in Science and Cellular Technologies with a thesis regarding the study of factors that could regulate the follicle development and the correct oocyte maturation. In 2010 Maria Cristina joined Biogenesi where she participated in research projects focused on the ultrastructure of human oocyte and started her training as Clinical Embryologist. She is currently working on confocal analysis of human oocytes and on time lapse microscopy to study early embryo development.
Publications
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- M. Cristina Guglielmo,.
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- D.F. Albertini,.
- M. Dal Canto,.
- F. Brambillasca,.
- M. Mignini,.
- E. De Ponti,.
- R. Fadini,.
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- M. Lain,.
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Dismorphic patters are associated with cytoskeletal alterations in human oocyte.
Hum Reprod. 2017 Apr 1;32(4):750-757.
Ultrastructure of human oocytes after in vitro maturation.
Mol Hum Reprod. 2016 Feb;22(2):110-8. doi: 10.1093/molehr/gav071
Double-strand DNA breaks and repair response in human immature oocytes and their relevance to meiotic resumption.
J. Assist Reprod Genet. 2015 Oct;32(10):1509-16. doi: 10.1007/s10815-015-0547-6
Oocyte maturation: gamete-somatic cells interactions, meiotic resumption, cytoskeletal dynamics and cytoplasmic reorganization.
Hum Reprod Update. 2015 Jul-Aug;21(4):427-54. doi: 10.1093/humupd/dmv011. Review.
Mechanistic foundations of the metaphase II spindle of human oocytes matured in vivo and in vitro
Human Reproduction.-2013, 28(12):3271-82.
Contributions of the actin cytoskeleton to the emergence of polarity during maturation in human oocytes.
Molecular Human Reproduction.-2013, doi:10.1093/MOLEHR/GAT085
The current challenges to efficient immature oocyte cryopreservation.
Journal of Assisted Reproduction and Genetics- 2013 Oct – DOI 10.1007/s10815-013-0112-0
DNA double strand breaks are associated with meiotic resumption failure in human GV-stage oocytes
Human Reproduction – 2012- 27 Suppl. 1, i189.
Human oocyte maturation in vitro
Int. J. Dev. Biol.- 2012- 56, 909–918.
Time-lapse imaging of immature human oocytes reveals a role for the oocyte cortex in germinal vesicle anchoring and meiotic resumption
Human Reproduction -2011- Vol. 26, Supplement 1--P176
In vitro maturation does not affect the geometry of the metaphase II spindle and cortical actin polarization of human oocytes
Human Reproduction - 2011 -Vol. 26, Supplement 1-P136-
New effective approach to blastocyst culture based on use of blastocyst medium from late day 2 of development.
Human Reproduction -2011- Vol. 26, Supplement 1- P123
Dr. Maria Cristina Guglielmo has degree in Medical Biotechnologies at the University of Rome “ La Sapienza”. She completed her PhD in Science and Cellular Technologies with a thesis regarding the study of factors that could regulate the follicle development and the correct oocyte maturation. In 2010 Maria Cristina joined Biogenesi where she participated in research projects focused on the ultrastructure of human oocyte and started her training as Clinical Embryologist. She is currently working on confocal analysis of human oocytes and on time lapse microscopy to study early embryo development.