Treatment with amniopatch of premature rupture of membranes after first-trimester chorionic villus sampling.

Abstract

OBJECTIVE:

To assess the amniopatch procedure when premature rupture of membranes occurs after first-trimester chorionic villus sampling (CVS).

STUDY DESIGN:

From May 2001 to June 2004, the amniopatch procedure was offered in cases of premature rupture of membranes after CVS when severe oligohydramnios was present (largest vertical pocket < 2 cm) and persistent (more than 1 week).

RESULTS:

The amniopatch was placed in five pregnancies at 12-18 weeks of gestation, resulting in amniotic fluid restoration in all but one pregnancy. In three pregnancies, fetal demise was observed at 1, 2 and 36 days after the procedure. The last procedure resulted in a healthy newborn.

CONCLUSION:

Although the amniopatch restored normal amniotic fluid levels in all cases, 4 of the 5 cases resulted in fetal demise.